Just as in the Incarnation, when the Spirit had formed the physical body of Christ in her virginal womb, likewise in the Cenacle, the Spirit comes to give life to His Mystical Body.
From this we learn, like the disciples, always stay close to Mother Mary.
Ask Her to help you to pray, especially in times of aridity and confusion.
Cenacle held every Friday except the 1st Friday of the month
Pope Benedict said that
“Wherever Christians gather
in prayer with Mother Mary,
the Lord gives His Spirit.”

You are encouraged to start the 1st Friday & 1st Saturday Devotions to the Sacred Heart of Jesus and the Immaculate Heart of Mary